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4-METHYLPYRAZOLE HYDROCHLORIDE

Product Name
4-METHYLPYRAZOLE HYDROCHLORIDE
CAS No.
56010-88-9
Chemical Name
4-METHYLPYRAZOLE HYDROCHLORIDE
Synonyms
FOMEPIZOLE HYDROCHLORIDE;4-METHYLPYRAZOLE HYDROCHLORIDE;Fomepizole/FomepizolechlorideHCl;4-Methyl-1H-pyrazole hydrochloride;4-Methylpyrazole hydrochloride alcohol dehydrogenase inhibitor
CBNumber
CB3106840
Molecular Formula
C4H7ClN2
Formula Weight
118.56
MOL File
56010-88-9.mol
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4-METHYLPYRAZOLE HYDROCHLORIDE Property

Melting point:
157-159 °C
storage temp. 
2-8°C
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M1387
Product name
4-Methylpyrazole hydrochloride
Purity
alcohol dehydrogenase inhibitor
Packaging
100mg
Price
$146
Updated
2024/03/01
Sigma-Aldrich
Product number
M1387
Product name
4-Methylpyrazole hydrochloride
Purity
alcohol dehydrogenase inhibitor
Packaging
1g
Price
$860
Updated
2024/03/01
Sigma-Aldrich
Product number
M1387
Product name
4-Methylpyrazole hydrochloride
Purity
alcohol dehydrogenase inhibitor
Packaging
500mg
Price
$504
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CHM0115061
Product name
4-METHYLPYRAZOLE HYDROCHLORIDE
Purity
95.00%
Packaging
100MG
Price
$634.02
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0115061
Product name
4-METHYLPYRAZOLE HYDROCHLORIDE
Purity
95.00%
Packaging
500MG
Price
$838.02
Updated
2021/12/16
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4-METHYLPYRAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

4-Methylpyrazole hydrochloride has been used:

  • as a cytochrome P450 2E1 inhibitor
  • as cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells
  • to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells

Biochem/physiol Actions

4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.

4-METHYLPYRAZOLE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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